Antczak Lab – Computational Biology of Ageing

Our mission is to apply computational biology approaches in the context of human and environmental health to reduce, refine, and replace the approaches to patient stratification, personalized medicine, complex drug/chemical interactions, regulatory decision making, and adverse outcome pathways.

Selected Publications

  • Bogaards, Fatih, Gehrmann, Thies, Beekman, Marieke, Lakenberg, Niko, Suchiman, E., de Groot C.P.G.M, Reinders, M.J.T., Müller, Roman-Ulrich, Antczak, Philipp*, Slagboom, Eline*. ”Multi-OMIC multi-tissue response to a mild lifestyle intervention in older adults represents reduced inflammatory response of subcutaneous fat tissue“ Nature Aging (submitted) (2024)
  • Bunte, Konstantin, Sevcan A. Bakkaloglu, Ayse Agbas, Ali Anarat, Bilal Aoun, Varvara Askiti, Karolis Azukaitis, Aysun Bayazit, Ipek Kaplan Bulut, Nur Canpolat, Dagmara Borzych-Dużałka, Ali Duzova, Sandra Habbig, Saoussen Krid, Christoph Licht, Mieczyslaw Litwin, Lukasz Obrycki, Fabio Paglialonga, Anja Rahn, Bruno Ranchin, Charlotte Samaille, Mohan Shenoy, Manish D Sinha, Brankica Spasojevic, Constantinos J Stefanidis, Enrico Vidal, Alev Yilmaz, Michel Fischbach, Franz Schaefer, Claus Peter Schmitt, Rukshana Shroff, Max Liebau*, and Philipp Antczak*. “Serum proteomics from the 3H-study suggests a role of complement activation for the lower risk of cardiovascular disease in patients on chronic Hemodiafiltration” eBiomedicine (submitted) (2024)
  • Muller, Roman-Ulrich, Hande Aydogan Balaban, Sita Arjune, Franziska Grundmann, Jan-Wilm Lackmann, and Philipp Antczak. "Developing serum proteomics based prediction models of disease progression in ADPKD." Nature Communications (submitted) (2024).